Is Priligy Suitable Medication For Me?

Priligy along with other few brands was marketed for the treatment of premature ejaculation in men aged between 18-64 years. The active ingredient of Priligy is Dapoxetine which has been shown to be effective. Priligy acts at the postsynaptic cleft resulting in inhibition of serotonin transporter, therefore causing a delay in the process of ejaculation. Priligy belongs to the class of selective serotonin reuptake inhibitor commonly known as SSRI family. Priligy was initially launched as an anti-depressant but it has got a difference from other members of this class. Unlike others, it absorbed and eliminated rapidly from the body. This property makes it far more suitable for treatment of premature ejaculation instead of depression.


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What is premature ejaculation?

Timing has to do a lot in a successful sexual relationship. Sex may not be pleasurable for you and your partner if the timing is not according to your desire of the climax. In many cases, men ejaculate early than the desire of either himself or his
partner. This is called premature ejaculation. It may lead to frustration and sometimes the situation may worsen and lead to embarrassment.
There is not a hard and fast rule that when a man should ejaculate during intercourse. But yes it is not fair enough that you ejaculate too soon, like just a few minutes after intercourse. The main problem associated with premature
ejaculation is that after ejaculation the erection is also lost and so is the chance to perform sex.
This problem prevails in 30-40%, men, at some stage in their life. It’s not a big issue if it happens once in a blue moon but you have to be concerned if its happening more occasionally.

The concept of premature ejaculation men. Girl on a white background holding a red clock closeup


Reasons behind Premature Ejaculation:

Chemical factor:

The exact reason behind premature ejaculation is not known. But one thing is for sure that brain chemistry has a role to play in it. A short time of ejaculation belongs to the low levels of serotonin hormone. Men having low levels of this hormone can
have the ejaculation disorders.
Emotional factors:

Emotional parameters can also play a major role in Premature Ejaculation disorder. They may be:
• Performance related anxiety.
• Depression
• Emotional problems in relation
• Stress
• Feeling of guilt

Erectile Dysfunctions after effect:

Premature ejaculation can become a problem in men suffering from erectile dysfunction. In such men, the penis does not maintain its erection during intercourse. Men suffering from erectile dysfunction are always under pressure of
maintaining an erection. This problem leads them to a habit of ejaculating early so that erection will be maintained. But this is not the solution, in fact, it is an invitation to
the next problem.
From the above discussion, it shows that treatment of erectile dysfunction disorder can help to alleviate this problem because the basic problem is of sustaining an erection. Drugs like ViagraTadalafilSpedra, and Levitra are helpful with erectile dysfunction.
Mechanism of Action of Priligy:

Though, the mechanism of action of Priligy regarding premature ejaculation is not clear. However, it is supposed that primarily works by blocking serotonin transport and afterwards increasing serotonin’s action at receptors, both presynaptic and
postsynaptic. The central nervous system is involved in regulating the human ejaculation in various ways. The spinal reflex is the originating point of the pathway of ejaculation. Thoracolumbar and lumbosacral level of the spinal cord is activated in response to stimuli from the male genital area. These signals are then forwarded to stem of the brain. The brain stem is prejudiced by a number of brain nuclei including preoptic and paraventricular nuclei. This mechanism has shown its effect in a clinical study conducted on a rat. Administration of a drug in the animal inhibits the ejaculatory reflex at the spinal level.


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5.00 out of 5
(3 product reviews)


Priligy has been proven to reduce premature ejaculation in clinical trials. It can increase the time until ejaculation by between 200% and 300%.

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Product Description

What is premature ejaculation?

Premature ejaculation is when a man experiences ejaculation soon after sexual contact; typically within two minutes of the beginning of sexual intercourse.  Average male ejaculatory latency time is seven minutes.  Men with PE often report emotional and relationship distress and it can be a difficult issue to talk about.

How do I take Priligy?

One Priligy tablet is to be taken with water one to three hours before sex.  Priligy can be taken with or without food but is not to be taken more than once per day.

In addition, Priligy is not intended for use every day, only when sexual activity is anticipated.

The recommended starting dose of Priligy is 30mg but if your condition does not improve after taking this dosage, you can be prescribed the 60mg dose.

Patient information leaflet

Always read the patient information leaflet before commencing treatment. Patient information can be found here.

3 reviews for Priligy

  1. habibi
    5 out of 5


    60mg Is the dogs, product very good and service is very good

  2. Chris
    5 out of 5


    This really works. 30g dose gave me a greater sense of control, but I still climaxed quickly. At 60g, however, I really noticed a difference. I felt like reaching orgasm very quickly (as normal!) then…decided not to and the drive to orgasm went away. More than a few minutes later I *decided* to orgasm. The second time shortly afterwards, I felt like a rock-star, just kept going. It was pretty miraculous. Also, it’s probably important to note that I felt no adverse effects. Not great for spontaneous use, of course–you have to plan ahead–but still a real game-changer for me. Recommended.

  3. Jonjoe
    5 out of 5


    This product works!

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When two drugs are contraindicated in administration, it should be followed in any way. There must be some harmful effect on the patient when contraindicated drugs are taken simultaneously. There are various drugs which are contraindicated with Priligy.
• Priligy should not be taken by men having problems of hepatic impairment.
• Patients taking CYP3A4 blockers like ketoconazole, ritonavir, and telithromycin.
• It is also contraindicated in patients who use the permanent pacemaker, have heart failure or other ischemic heart problems.
• Patients taking selective serotonin intake inhibitors or anti-depressants.
You can continue the use of a specific medication after 7 days of discontinuation of its contraindication.

Adverse effects of Priligy:

A few rare adverse effects associated with priligy are:
• Dizziness
• Mild headache
• Feeling of being sick
• Sudden onset of sleep
• Bowel movement problem

Some commonly occurring side effects of Priligy are:
• Feeling of irritation
• Difficulty with maintaining an erection
• Flushing or increased sweating
• Constipation
• Diarrhoea
• Pain in the digestive tract
• Dreaming
• Sleepiness or tiredness
• Respiratory tract congestion
• Increased blood pressure
• Inability to concentrate
• Decreased sexual desire

• Poor digestion
• Dryness of mouth

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There are also some uncommon side effects which occur rarely like in 1 to 10 men in 1000 users:
• Dizziness
• Paronia or overexcitement
• Arrhythmia
• Low sex desire
• Depression
• Teeth grinding
• Problems with taste buds
• Itching
• Decreased blood pressure
If you feel that any of the side effects gets serious, immediately discontinue the medication and consult your doctor or pharmacist.
Drug interactions:
Phosphodiesterase inhibitors: (PDE5 inhibitors)
Most of the men that have premature ejaculation also have erectile dysfunction issues. While treating these patients, drug interactions between Sildenafil and phosphodiesterase should be considered. The PDE5 inhibitors drugs such as Cialis or
Viagra does not have any effect on pharmacokinetic properties of Priligy. This conclusion is based on the study of the Dresser study conducted in 2006.


How to take Priligy?

Sometimes extra care is needed in order to take a medicine. Some medications are not proper in every condition. Priligy is also one of these medicines. Before taking Priligy it is important to consider the situations given below:
• Tendency to faint
• Any kind of heart disorder
• Blood clotting
• Epilepsy
• If you have any history of mental health, depression or bipolar disorder
• Glaucoma
• If you have any kidney disorder
• Liver disorders
• Any kind of allergic reactions to medicine
• If you are taking any non-prescription medication then it has to be considered for drug interactions
Whatever medicine are you taking, you should first read the information provided on the leaflet in the pack. It can provide the basic information about medicine like how, when and with what medicine should be taken. It also tells about the possible side
effects and contraindications.
Take Priligy according to the prescription and advice of the doctor. Priligy should be taken with water. Drink at least a full glass of water.
The recommended dose of Priligy is 30mg, 2 to 3 hours before sex. The dose can be increased under the supervision of a doctor to 60mg if the results are not satisfactory at a lower dose. But the dose adjustment should only be done by
prescriber after considering the side effects. Never take the tablet twice a day. It should be taken only if you are planning to have sex.
Priligy can be taken with food or on an empty stomach.

Conclusively, Priligy is a safe medication and can be used for the treatment of premature ejaculation after consulting with your doctor. Your doctor will prescribe the dose according to needs and health condition of your body.


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