The Dangers Of Using Viagra With Poppers

Short facts about Viagra:

✓ Viagra is the brand name containing the active compound Sildenafil, the first drug discovered 20 years ago for erectile dysfunction treatment.
✓ Since its launch as a prescription in 1998, 40 million men around the globe have used Viagra at least once.
✓ The researchers of Viagra wanted to discover a medicine for the cure of cardiovascular diseases, instead, they developed a medicine which could reverse impotence or erectile dysfunction for the first time.
✓ Viagra is one of the most counterfeited medicines in the world.

Short facts about Poppers:

✓ Poppers are a group of chemical substances belonging to alkyl nitrites, first used to treat angina (in 1867) and now as a room-odorisor.
✓ They are usually sold in small bottles, in the form of liquids that produce a vapour that can be inhaled.
✓ They can be found for sale in some as sex shops, joke shops and occasionally in pubs, tobacconists, music stores, and clothes shops for prices starting at about £3.50 a bottle.
✓ When inhaled, they get warm sensations, head-rush, and increased heart rate.

How does Viagra help Erectile Dysfunction

Viagra is used for a sexual disorder called erectile dysfunction. Viagra has an effect on the blood flow to the penis, maintaining the erection firm and improving the quality of the sexual intercourse. Many men wonder how long should they last in bed. Every man wants to be satisfied in bed and to offer satisfaction to his partner. Viagra can help in either of the circumstances, due to the fact it has an onset of up to 1 hour and a duration of up to 5 hours.
Viagra is a prescribed medicinal product, containing sildenafil and is only licensed for the treatment of adult men with erectile dysfunction.
Until 1998, no effective oral therapy for erectile dysfunction was available. The only treatments available were highly cumbersome or invasive, and many men found them unacceptable as solutions to the problem of achieving or maintaining a satisfactory erection. Sildenafil citrate was the first oral agent to be introduced for the treatment of erectile dysfunction, thanks to the researchers from Pfizer. In order for Viagra to be effective, you must be sexually stimulated.

 

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How long should I last?Doubtful young man sitting and gesturing with hands isolated on white background

No manual defines how much time a good sexual encounter lasts.
According to the International Society for Sexual Medicine, there is no defined timing for how long should sex last. Couples may have different views related to this topic, depending on their age, their relationship status, their health status, their preferences and the circumstances, and Viagra has not been proven to change this.

According to the same Institution, the frequency of sex is also different depending on many factors. The frequency can change over time, depending on the evolution of the relationship, of the chemistry of the partners, their imagination towards stimulation of their partner, their work/personal life balance, if they are single, married or partnered and so on.

When the use of Viagra became a concern?

The use of Viagra became a concern when there was evidence that healthy people are starting to use it as a recreational drug or as a neuroenhancer, that means to stimulate brain processes. This is similar to doping in sport and it is not recommended or approved.
Drug misuse studies were conducted and they revealed the fact that Viagra is used ‘’off-label” to counterbalance the effect of difficult penile erection caused by the use of other illicit drugs, for example, and even by people not suffering from erectile dysfunction to obtain better sexual performances.
This phenomenon was compared to one of the athletes who make use of doping substances based on their belief that most of their competitors are doping and their fear that they can only win with the support of performance enhancers. Similarly, young people use cognitive enhancers and recreational drugs because they believe that others are doing the same and that they must do so to remain competitive. 7
This is again a matter of personal choice and personal beliefs. It is a fact that people’s belief about the drug use of their peers has a large impact on their own willingness to use those drugs. Some scientists speculate that this will soon become a frequent practice. An informal survey published by a scientific magazine underlined the fact that one in five people are misusing drugs for non‐medical reasons to stimulate their focus, concentration or memory: 62% had used methylphenidate, 44% had used modafinil and 15% had used beta‐blockers such as propranolol. 7 Sildenafil appears to be used quite often by healthy young men and in the gay community together with other illicit drugs. In a survey conducted in London nightclubs, the responders taking Viagra as a recreational drug reported positive effects for enhanced sexual desire and lovemaking.
Negative effects, such as headaches, genital soreness, and intoxication were overlooked and surprisingly, all responders said they would take the drug again! This had usually been obtained from friends, dealers, sex shops and public restrooms.
The combination with Poppers is particularly dangerous as both drugs dilate blood vessels, which can result in a dangerous drop in blood pressure and possibly myocardial infarction or stroke. 8

Why are Poppers such a major concern?

Because according to police reports, they are responsible for some cases of death due to methaemoglobinaemia, where an abnormal amount of methemoglobin – a form of haemoglobin – is produced in the blood.
Also if you are suffering from heart failure or if you have blood pressure problems, poppers can be very dangerous due to their effect on lowering blood pressure and increasing heart rate.
The Advisory Council on the Misuse of Drugs (ACDM) is sending constant messages regarding the misuse of poppers.
They have been used recreationally since the 1970s even if they are indicated for other uses.
Among the effects, poppers produce it was noted: head rush, relaxation of the muscles in the vagina and anal sphincter. So some users take them, in the words of the ACMD’s advice to the Government: “For their muscle relaxing effects, to facilitate anal and vaginal sex. Users claim that poppers help increase libido.”
Fatal adverse effects can appear if you take Poppers with Viagra especially if Viagra is bought from illegal sources as it is usually counterfeited.

What are the dangers of using Viagra with Poppers?

The most dangerous effect of the combination is a serious drop in the blood pressure that can be fatal. By far the most common side effect is a pounding headache. The combination of poppers and Viagra can also produce sickness or dizziness, or even syncope.
Poppers cause chemical burns if you get the liquid on your skin and don’t wash it off with water quickly enough. In rare cases, there are also some reports that poppers can cause impaired vision or sight loss, although this may be reversible if you stop using them. If you abuse them heavily you can experience crusty yellow facial skin lesions around the lips, nose and mouth

The best advice a man can get when intending to use Viagra are…

DO NOT take Viagra from unknown sources. Buy Viagra from a registered online Pharmacy or your GP. There is a high rate of Viagra counterfeit reported.
Also, you should not use Viagra with any other local or oral treatments for erectile dysfunction.
You should NEVER take Viagra with poppers.
Viagra takes longer to start working if you take it with a heavy meal.
Also, drinking alcohol can temporarily impair your ability to get an erection.
We are advising not to drink excessive amounts of alcohol if you desire an immediate and efficient effect of Viagra.
You should not take Viagra more than once a day.
You should take Viagra about one hour before you are planning to have sex.
Swallow the tablet whole with a glass of water.
And just relax and enjoy the moments.

Be careful at any adverse effects

An oral overdose of any erectile dysfunction drugs manifests in priapism, an erection that lasts for several hours. Priapism can happen if too much blood flows into the penis, causing it to swell. When taking too many doses of Viagra, the appearance of priapism is a major risk.
Start with your 50 mg dose of Viagra or with the dose that your doctor indicated.
Do not take Viagra more than once a day!
Priapism is a medical emergency that requires IMMEDIATE medical attention.
Another risk associated with Viagra consumption is a drop in the blood pressure. The first symptoms when experiencing a drop in the blood pressure is feeling weak, dizziness and nausea.
In very severe cases, persistent low blood pressure over a period of time can substantially reduce the amount of oxygen that reaches important parts of the body, like the heart and brain. Eventually, these organs can become damaged. You can suffer a stroke or a cardiac arrest.
Let’s not forget the fact that Viagra originally entered into clinical studies as a medication intended for lowering high blood pressure. So try to carefully monitor your blood pressure during the period when you are intending to use Viagra. Other common adverse reactions include a headache, flushing, dyspepsia, nasal congestion, dizziness, nausea and altered vision.
As dizziness was reported in clinical trials, it is better not to drive or to manipulate any operating machinery immediately after taking Viagra.

So, can you treat erectile dysfunction with Viagra?

We take erectile dysfunction as a serious condition with a markedly negative impact on quality of life.
Viagra is intended and approved for the treatment of erectile dysfunction.
However, it will not cure it. It will keep control of the penile erection, it will make your sex experiences better and can make you feel comfortable again.
It can be used in the same manner by the young patient and the aged patient.
But remember that the definition and the possible causes for the onset of the erectile dysfunction are different for every guy.
Even if organic causes are predominant for the onset of erectile dysfunction, other pathologies such as diabetes mellitus or renal failure are causing erectile dysfunction with a high frequency.
Risk factors for developing erectile dysfunction include age, diabetes, hypertension, obesity, lack of exercise, dyslipidemia, smoking, depression, lower urinary tract symptoms, and pelvic surgery.

Important numbers when using Viagra

Viagra uses results in an average time to onset of erections of up to 60 minutes.
After oral ingestion, Viagra is completely “out of your system” in 20 Hours, but it’s effectiveness becomes lower after approximately 4 hours.
Viagra will allow a firmer erection with less stimulation and will make possible a few more erections during the interval of 4-5 hours postdose. It will also decrease your refractory time, the time required to achieve a subsequent erection after ejaculation.

Where to buy Viagra?

Buy Viagra from a trusted source, like Assured Pharmacy. Because only when buying from an approved and registered pharmacy, you can be certain about the quality of the medicinal products that you ordered. Viagra can be delivered directly to your door after you fill in a short medical questionnaire. Our doctor will review your questionnaire to confirm if Viagra is the appropriate medicinal product for you.

 

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Product Description

How does Viagra and Sildenafil work?

Viagra (Sildenafil) helps men to get and maintain an erection when sexually stimulated and/or excited. The medicine relaxes the blood vessels in the penis which results in more blood flowing to the penis when you are sexually excited.

How do I take it?

You should take Viagra (Sildenafil) approximately 1 hour before planning to have intercourse. Within a window of between 30 minutes and 4 hours after you take the medicine, it will be easier to keep and maintain an erection when you are sexually excited. If you take this medicine after a meal with a high fat content it may take a little longer to start working. This medicine will only work when you are sexually excited. You won’t get an erection just by taking Viagra (Sildenafil).

Dosage

The standard recommended dose for Viagra (Sildenafil) is 50mg and this will be suitable for most people.  If this dose is not effective, you can try 100mg and if 50mg gives you side effects you can also reduce the dose to 25mg tablets.

You must not take more than 100mg daily of Sildenafil/ Viagra. Clinical trials have been conducted in patients taking up to 200mg sildenafil and it was found that ‘doses of 200mg did not result in increased efficacy but did increase the incidence of adverse reactions (headache, flushing, dizziness, dyspepsia, nasal congestion, and altered vision).’

In addition, in patients taking more than 100mg daily, there have been reports of rhabdomyolysis (a breakdown in skeletal muscle tissue the byproducts of which can lead to kidney failure), visual perception changes, vertebral artery dissection (a tear in the artery supplying blood to the brain), heart attacks and aggressive behaviour.

If the 100mg strength doesn’t work for you, there may be alternatives you can try and we recommend that you call us for a free consultation with our pharmacist or doctor to discuss any underlying conditions you may have. We recommend that all men taking medicine for erectile dysfunction have regular tests for blood pressure, cholesterol, diabetes and hormone imbalances. For instance, it may be that by fixing a hormone imbalance such as testosterone, your Viagra medication will be even more effective.

In addition, drug manufacturers do not advise patients to split tablets in half to get the correct dosage as they cannot guarantee that the active ingredient will be distributed evenly throughout the tablet.  For instance, if you cut a 100mg tablet in two, you may find that you get 80mg in one half of the tablet and 20mg in the other half leading to either an overdose (increased risk of side effects) or a suboptimal dose (the medication may not work).

It is important that you choose the correct dose for you. If you wish to talk to our pharmacist or doctor about this, please contact us in the pharmacy on 01625 460621 or email [email protected]

Side Effects

Viagra (Sildenafil) is normally well tolerated, however, side effects can include:

  • Headache
  • Dizziness
  • Nausea

Side effects normally subside after a few hours, however, if you experience a prolonged or painful erection (longer than 4 hours), then you must contact your doctor immediately.

Drug interactions

There are a number of medicines which interact with Sildenafil/ Viagra. For an exhaustive list please see the patient information leaflet (see section below) or call us in the pharmacy to discuss your specific situation. The main drug interactions are listed here:

Recreational drugs such as ‘poppers’ or amyl nitrate
Alpha blockers used for urinary retention or blood pressure problems (eg Flomax or Cardura)
Anti- arrhythmic drugs such as disopyramide
Antibiotics such as erythromycin
Antifungals such as itraconazole
Antivirals such as drugs used to treat HIV
Bosentan
Cobicistat
Calcium channel blockers to treat blood pressure and angina such as amlodipine
Dapoxetine (Priligy – used to treat premature ejaculation)
Grapefruit juice**
Nicorandil
Nitrates
Riociguat
Cimetidine (to treat stomach ulcers)

Please do not take Sildenafil/Viagra if you have taken any of the above drugs within the last 60 days without first consulting with either us in the Pharmacy ([email protected] / 01625 460621) or via email with our doctor [email protected]

**We advise not to take Sildenafil/Viagra with grapefruit juice as the blood concentration of Sildenafil will possibly be increased resulting in side effects.

Patient Information Leaflets

Please click here for the patient information leaflet for Viagra.

For Actavis Sildenafil please see the following leaflets: 100mg, 50mg, 25mg.

Storing Medicines Safely

Please keep your medicine out of the reach of children and store at room temperature.  Unwanted medicine can be disposed of by returning it to any local pharmacy or indeed to us here for us to dispose of it for you.

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In summary …

Advantages of Viagra use are clear: a reasonably short time of action onset, reliable efficacy, good tolerability, high selectivity for the site of action, lack of central nervous system effects, rapid absorption that yields prompt onset of action and a plasma half-life that produces an appropriate duration of action while avoiding accumulation upon repeated once-daily use.
Please take Viagra exactly as your doctor or pharmacist advised. Do not mix it with any other drugs that were not prescribed to you.
The combination with poppers can lead to a significant decrease in the blood pressure and also a temporary loss of vision.
It is very important to monitor your blood pressure all the time when using Viagra.
Start your treatment with 50 mg of Viagra. Depending on the response, your dose may be modified.

 

 

References:

1. https://www.accessrx.com/blog/erectile-dysfunction/7-cool-facts-about-viagra/#
2. https://www.drugs.com/slideshow/viagra-little-blue-pill-1043#
3. Efremov EA et al. PDE-5 inhibitors: Patients preferences
4. https://www.independent.co.uk/news/uk/so-what-exactly-are-poppers-a7052141.html
5. K Hatzimouratidis- Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence
6. http://www.issm.info/sexual-health-qa/what-is-the-normal-frequency-of-sex
7. Jane C. Lucke et al. Academic doping or Viagra for the brain http://embor.embopress.org/content/12/3/197
8. Wui Ling Chan et al. Significant misuse of sildenafil in London Nightclubs
9. Jackson G, Gillies H, Osterloh I (2005) Past, present, and future: a 7‐year update of Viagra (sildenafil citrate). Int J Clin Pract 59: 680–691
10. Gruenwald I, Leiba R, Vardi Y (2009) Effect of sildenafil on middle‐aged sexually active males with no erectile complaints: a randomized placebo‐controlled double‐blind study. Eur Urol 55: 969–978

Assured Pharmacy is not liable for the currency or accuracy of the information contained in this blog post. For specific information about your personal medical condition, please contact our doctors or pharmacists for advice on [email protected]