What is it?

Mounjaro is designed to support your weight loss journey on a weekly basis. Enhanced by a balanced, calorie-conscious diet and regular physical activity, Mounjaro maximises its effectiveness, ensuring safe and steady weight loss progress.

• Weekly injection that suppresses appetite and reduces cravings.
• With lifestyle changes around 96% of people lose weight.
• Suitable for adults with a BMI of 30 or above, or 27 and above with a weight related condition.

It is important to continue to follow the advice on diet and exercise given to you by prescriber.

Does it work?

Clinical trials have shown that on average, patients lost up to 21% of their original weight on the highest dose of Mounjaro (15mg). Most adults (96%) can also expect to lose at least 5% of their body weight when using Mounjaro (https://clinicaltrials.gov/study/NCT04184622)

Mounjaro in the UK

Mounjaro has recently been approved as a weight loss treatment in the UK. It is now available on prescription at Assured Pharmacy.

How to use it?

Administer Mounjaro via injection once weekly into your abdomen, thigh, or upper arm. Tailored to your treatment stage, Mounjaro is available in various doses.

Commencing with a 2.5mg initial dose, subsequent increments of 2.5mg are administered until reaching 15mg. This gradual dosage escalation ensures manageable adaptation to any potential side effects. Each dosage level is maintained for four weeks before advancing to the next.

• Read the Instructions for Use that come with Mounjaro.
• Use Mounjaro exactly as your healthcare provider says.
• Each pen is for one patient only and should not be used by anyone other than you.

Choosing when to use Mounjaro?

You should inject Mounjaro® on the same day every week. You can take it at any time of day. You might want to set a reminder on your phone, so you don’t forget what day you normally take it.

• You can use your pen at any time of the day, with or without meals.
• Use Mounjaro on the same day each week.
• To help you remember, when to use Mounjaro, you may wish to tick the day of the week when
• you inject your first dose on the box that your pen comes in, or mark it on a calendar.
• If necessary, you can change the day of your weekly injection, as long as it has been at least 3
• days since your last injection.
• After selecting a new dosing day, continue with once-a-week dosing on that new day

Missed a dose of Mounjaro?

If you happen to miss a dose of Mounjaro, it's recommended to administer the missed dose within 4 days of the scheduled time. Please strive to take it promptly upon realising the oversight.

In the event that more than 4 days have transpired since the missed dose, it's best to skip it and resume your regular dosing regimen on the scheduled day. Be cautious not to double up doses within a 3-day period.

Storage and Disposal

• Dispose of your used pen needles in a sharps disposal container right away after use, do not dispose of loose pen needles in your household waste.
• Dispose of the used pen in your household bin after you have removed the needle.
• Do not recycle your used sharps disposal container.
• Sharps disposal container should be taken to a local pharmacy for disposal once full.
• Ask your doctor, pharmacist or nurse about how to dispose of medicines you no longer use.

Potential side effects of Mounjaro

As with any medication, certain individuals may experience side effects while using Mounjaro. Some very common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Constipation

The side effects of Mounjaro typically improve over time as your body adjusts to the treatment. You may find that side effects are most noticeable during the dose escalation phase and tend to be mild. As your body acclimates to the treatment, these side effects are likely to diminish and eventually disappear.

Establish a consistent injection schedule by administering Mounjaro on the same day each week to give your body regular breaks between treatments. To effectively manage side effects, consider the following strategies:

• Consume smaller, more frequent meals
• Stop eating when you feel full
• Stay hydrated by drinking plenty of water
• Avoid consuming fatty foods
• If feeling nauseous, sip water and opt for plain foods such as toast, crackers, or rice
• Increase fiber intake to alleviate constipation
• Maintain a regular exercise routine
• For headaches, you may take paracetamol

Remember to consult with your healthcare provider if you experience persistent or severe side effects.

Mounjaro vs Wegovy

Mounjaro® is more effective than Wegovy®. A clinical trial over a 72-week period showed that 96% of the participants taking Mounjaro® (on the highest dose) lost 5% or more of their starting body weight. In a similar trial, 84% of people taking Wegovy® on the highest dose lost at least 5% of their body weight.

https://clinicaltrials.gov/study/NCT04184622?tab=results#results-overview
https://www.ema.europa.eu/en/documents/overview/wegovy-epar-medicine-overview_en.pdf